Key result
Pregnancy is not linked to increased SVD in women 35 or younger with bioprostheses.
Why the study?
Does pregnancy increase the risk of structural valve deterioration in young women with bioprostheses?
Population
237 female patients aged 35 years or less who received 255 biological prostheses between 1972 and 1992.
Comparison
Pregnancy after bioprosthetic valve implantation. vs No pregnancy after bioprosthetic valve…
Design
Cohort
Follow-up
Mean 6.8 years for nonpregnant group, 7.9 years for…
Authors
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No increased SVD risk observed with pregnancy; leaves open optimal valve selection pending prospective confirmation.
Cohort (n=237)
Does pregnancy increase the risk of structural valve deterioration in young women with bioprostheses?
Absolute Event Rate: 51% vs 41%
p-value: p=NS
Pregnancy does not significantly accelerate structural valve deterioration in young women with bioprostheses, supporting their use in patients desiring future uncomplicated pregnancies.
Jamieson et al. (1995) conducted a cohort in Biological prostheses (n=237). Pregnancy vs. No pregnancy was evaluated on Structural valve deterioration (SVD) (p=NS). Pregnancy did not significantly influence the incidence of structural valve deterioration in women aged 35 years or less with bioprostheses (51% vs 41%; p=NS).
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