Key result
Adding troponin to PESI improves predictive accuracy for 30-day mortality over PESI alone.
Why the study?
Does the addition of biomarkers (Troponin I and D-dimer) to the PESI score improve the prediction of 30-day mortality in normotensive patients with acute pulmonary embolism?
Observational (n=411)
Yes
Does the addition of biomarkers (Troponin I and D-dimer) to the PESI score improve the prediction of 30-day mortality in normotensive patients with acute pulmonary embolism?
Effect estimate: AUC 0.85 vs 0.80
Adding troponin to the PESI scoring system improves the predictive accuracy for 30-day mortality in normotensive patients with acute pulmonary embolism.
No takes yet. Share an insight, caveat, or question.
May refine risk stratification in normotensive PE; leaves open prospective validation before practice change.
Singanayagam et al. (2010) conducted an observational in acute pulmonary embolism (n=411). Addition of Troponin to PESI score vs. PESI score alone was evaluated on 30-day mortality (AUC 0.85 vs 0.80). Addition of troponin to the Pulmonary Embolism Severity Index (PESI) improved the predictive accuracy for 30-day mortality compared to PESI alone (AUC 0.85 vs. 0.80).
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