Key result
Cerebral rSO2 increases during pediatric CPB cooling but lacks correlation with blood pressure or pump flow.
Population
50 pediatric patients undergoing congenital heart surgery, ages ranging from 6 days to 168 months.
Design
Cohort
Follow-up
During cardiopulmonary bypass
Authors
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NIRS should not yet guide perfusion targets in pediatric CPB; hypothesis-generating for cerebral autoregulation independent of standard parameters.
Observational (n=50)
Cerebral regional oxygenation measured by NIRS does not significantly correlate with mean blood pressure or pump flow during pediatric cardiopulmonary bypass, suggesting adequate perfusion can be maintained despite blood pressure fluctuations.
Haydın et al. (2012) conducted an observational in Congenital heart disease requiring surgery with cardiopulmonary bypass (n=50). Cardiopulmonary bypass parameters (lactate, pump flow, hematocrit, pCO2, mean blood pressure) was evaluated on Correlation between cerebral rSO2 and lactate, pump flow, hematocrit, pCO2, and mean blood pressure during CPB. During pediatric cardiopulmonary bypass, cerebral rSO2 significantly increased during cooling (P<0.05) but showed no significant correlation with mean blood pressure, pump flow, hematocrit, or pCO2.
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