Key result
Decreased cerebral NIRS during CPB is linked to higher APACHE-II scores and mortality.
Why the study?
This study aimed to investigate the correlation between cerebral perfusion changes and mortality rate in individuals undergoing adult cardiac surgery.
Do cerebral perfusion changes measured by NIRS correlate with mortality scores and mortality in adults undergoing cardiac surgery with CPB?
Population
91 adult individuals who underwent open heart surgery with CPB
Comparison
Cerebral perfusion monitored via NIRS at four operative intervals
Design
Prospective cohort study
Authors
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NIRS desaturation during CPB may flag higher-risk patients; hypothesis-generating and requires prospective trials before guiding practice.
Cohort (n=91)
Do cerebral perfusion changes measured by NIRS correlate with mortality scores and mortality in adults undergoing cardiac surgery with CPB?
Effect estimate: C index 0.871 (95% CI 0.660-1)
p-value: p=0.010
Decreases in cerebral perfusion measured by NIRS during cardiopulmonary bypass correlate with higher postoperative mortality prediction scores and actual mortality.
Şen et al. (2019) conducted a cohort in Open heart surgery with cardiopulmonary bypass (n=91). Cerebral perfusion changes (NIRS) was evaluated on Mortality (C index 0.871, 95% CI 0.660-1, p=0.010). Decreases in cerebral near-infrared spectroscopy values during cardiopulmonary bypass were associated with increased APACHE-II scores and predicted mortality (APACHE-II C index 0.871; P=0.010).
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