Key result
Surgical resection treats rare primary cardiac synovial sarcoma causing tricuspid stenosis and right heart failure.
Case Report (n=1)
This case highlights the importance of early echocardiography in young patients with unexplained systemic symptoms and right-sided heart failure to diagnose rare primary cardiac sarcomas.
Raises awareness for rare tumors in atypical right heart failure; extends sparse case series on cardiac synovial sarcoma.
Primary cardiac sarcomas are rare, aggressive malignant tumors with high recurrence rates and poor prognosis.Their initial presentation is often vague, contributing to diagnostic delay and rapid clinical deterioration.We report the case of a 32-year-old man who presented with gastrointestinal symptoms and constitutional features, initially suggesting a hepatobiliary or infectious cause.As his condition progressed, signs of right-sided heart failure emerged, prompting transthoracic echocardiography, which revealed a large right atrial mass causing tricuspid inflow obstruction and a significant pericardial effusion.Surgical resection confirmed biphasic synovial sarcoma, a subtype previously described in small case series.Despite an initially uncomplicated postoperative course, he subsequently developed atrial flutter with associated left ventricular dysfunction, necessitating cardioversion.Anthracycline toxicity remains a possible contributing factor.This case underscores the importance of maintaining a broad differential diagnosis in young patients with unexplained systemic symptoms and highlights the diagnostic value of early echocardiographic assessment when right-sided cardiac involvement is suspected.It also reinforces the need for multidisciplinary management given the tumor's aggressive behavior and potential for rapid clinical decline.
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Baig et al. (2026) conducted a case report in Primary cardiac sarcoma (biphasic synovial sarcoma) (n=1). Surgical resection and chemotherapy was evaluated. A 32-year-old man presenting with systemic symptoms and right-sided heart failure was diagnosed with a rare primary cardiac synovial sarcoma causing tricuspid stenosis, managed with surgical resection.
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