Clinical review demonstrates impaired left atrial strain in heart failure with preserved ejection fraction, indicating its diagnostic value.
Key Points
To review the pathophysiological role, diagnostic utility, and prognostic implications of left atrial strain in patients with heart failure with preserved ejection fraction.
Synthesized echocardiographic evidence assessing left atrial reservoir, conduit, and contractile function.
Evaluated myocardial deformation imaging using two-dimensional speckle-tracking echocardiography across clinical cohorts.
Left atrial reservoir strain consistently deteriorates alongside worsening diastolic dysfunction and elevated left ventricular filling pressures.
Impairments in left atrial mechanics independently correlate with increased rates of heart failure hospitalization and adverse cardiovascular events.