Review demonstrates distinct stroke risk profiles and higher bleeding rates in Asian cohorts, highlighting the need for tailored anticoagulation therapies.
Key Points
To evaluate the epidemiology, clinical presentations, and therapeutic management of atrial fibrillation across Asian populations.
Synthesized regional registry data, clinical trials, and epidemiological cohorts evaluating atrial fibrillation in Asia.
Assessed comparative rates of ischemic stroke, systemic thromboembolism, and intracranial bleeding relative to non-Asian populations.
Identifies an accelerating disease prevalence and incidence attributed to population aging and lifestyle transitions across Asia.
Documents a higher susceptibility to anticoagulant-related bleeding complications, particularly intracranial hemorrhage, necessitating individualized dosing and stroke-prevention strategies.