What does this research mean for the field?

Phototherapy in full-term neonates is associated with a decrease in bone mineral density in the arms and lumbar spine, despite causing no significant changes in serum calcium. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Investigate whether phototherapy induces measurable alterations in calcium-phosphate metabolism, body composition, and bone mineral density in full-term neonates.

September 14, 2026Egyptian Pediatric Association GazetteOpen Access

Effect of phototherapy on calcium metabolism and bone mineral density in full-term neonates (Pilot study)

View Full Paper

Ask AI

Bookmark

Investigate whether phototherapy induces measurable alterations in calcium-phosphate metabolism, body composition, and bone mineral density in full-term neonates.
Conducted a pilot comparative study of 40 full-term neonates aged 2 to 8 days, divided into 20 cases receiving phototherapy and 20 controls.
Performed dual-energy X-ray absorptiometry (DXA) scans at baseline and at one-month follow-up.
Evaluated serum calcium, magnesium, phosphorus, vitamin D, parathyroid hormone, and alkaline phosphatase at baseline and 48 hours after phototherapy initiation.
Hypocalcemia incidence shifted non-significantly from 15% pre-phototherapy to 21.1% post-phototherapy, with no significant differences in median magnesium, alkaline phosphatase, or vitamin D.
A statistically significant decrease occurred in mean serum phosphorus at follow-up across both groups.
DXA analysis demonstrated a statistically significant decrease in bone mineral density at the arms and lumbar spine (L1–L4) following phototherapy.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Pilot comparative study reveals reduced bone mineral density in full-term neonates following phototherapy, suggesting potential skeletal side effects during neonatal jaundice treatment.

Cite This Study

Khamis et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b2530926e14a848b0bbd https://doi.org/10.1186/s43054-026-00619-z

View Full Paper

Ask AI

Bookmark

Implication

Pilot comparative study reveals reduced bone mineral density in full-term neonates following phototherapy, suggesting potential skeletal side effects during neonatal jaundice treatment.

Effect of phototherapy on calcium metabolism and bone mineral density in full-term neonates (Pilot study)

Key Points

Discussion

Implication

Cite This Study

Effect of phototherapy on calcium metabolism and bone mineral density in full-term neonates (Pilot study)

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider