Fatal Metformin Poisoning: Adolescent Case Report

Metformin is a biguanide oral hypoglycemic agent used for non-insulin dependent diabetes mellitus. Lactic acidosis still the most important and dangerous side effect of acute and chronic metformin use, its mortality can reach up 50%. Metformin poisoning in children remains rare and is very rarely reported in the literature. The curative treatment is based on early extrarenal purification by haemodialysis or haemodiafiltration. However, the prognosis of high doses of metformin can be fatal. We are reporting the case of a 14-year-old female patient who intentionally overdosed on metformin, resulting in lactic acidosis and death.