Key result
Cigarette smoking is linked to ~45% higher WBC counts and elevated cholesterol versus non-smokers.
Why the study?
The study was conducted to investigate the effect of cigarette smoking on lipid profile and complete blood count parameters.
Does cigarette smoking alter lipid profiles and hematological parameters compared to non-smoking?
Observational (n=70)
No
Does cigarette smoking alter lipid profiles and hematological parameters compared to non-smoking?
Absolute Event Rate: 9.82% vs 6.78%
Cigarette smoking is associated with elevated cholesterol and altered hematological parameters, including increased platelet counts.
No immediate practice change from cross-sectional data; leaves open causality and need for prospective confirmation.
The effect of cigarette smoking on lipid profile and CBC (Complete Blood Count) of blood was investigated in this study. Spectrophotometric methods were used to estimate the amounts of nicotine, cholesterol, triglycerides, and HDL-cholesterol. The findings revealed that cigarette smokers and the duration of smoking had significantly higher levels of nicotine and cholesterol when compared to non-smokers. The data also revealed differences in the contents of hematological parameters between smokers’ and non-smokers’ blood samples, with high counts of WBC, MCHC, HGB, and PLT clearly visible in the smokers’ samples. However, there was no discernible effect on RBC, MCV, or MCH counts in the trial. Smoker samples had high PLT values (243.8 ± 84.26), while non-smoker samples had lower PLT values (229.3 ± 30.07 on average).
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Hasan et al. (2022) conducted an observational in Healthy (Smokers vs Non-smokers) (n=70). Cigarette smoking vs. Non-smokers was evaluated on White blood cell (WBC) count. Cigarette smokers had higher white blood cell counts (9.82 vs 6.78 x10^9/L) and cholesterol levels (151.9 vs 144.3 mg/dL) compared to non-smokers.
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