Key result
Multimodality neuromonitoring during CABG linked to ~51% lower serious brain injury risk versus no monitoring.
Why the study?
Does multimodality neuromonitoring reduce the incidence of serious brain injury in adults undergoing CABG?
Cohort
Does multimodality neuromonitoring reduce the incidence of serious brain injury in adults undergoing CABG?
Absolute Event Rate: 3% vs 6.1%
p-value: p=0.03
Multimodality neuromonitoring during CABG is associated with a significant reduction in serious brain injury, primarily by reducing nonembolic diffuse injuries.
Neuromonitoring during CABG should not yet change practice; leaves open whether it reduces serious brain injury in randomized settings.
This study was a retrospective examination of the influence of multimodality neuromonitoring on the incidence of serious brain injury associated with a common type of adult cardiac surgery, coronary artery bypass grafting (CABG). Multichannel EEG, cerebral oximetry, and transcranial Doppler ultrasound were used to detect and correct imbalances in cerebral perfusion and oxygenation. Imbalances were detected in 59% of the cases and successfully corrected in all but 2%. In the absence of neuromonitoring, the expected incidence of serious brain injury is 6.1%. With neuromonitoring, the actual observed incidence was 3.0% (P= 0.03). The apparent improvement can be attributed primarily to a reduction in the number of nonembolic diffuse injuries.
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Harvey L. Edmonds (2005) conducted a cohort in Coronary artery bypass grafting (CABG). Multimodality neuromonitoring (multichannel EEG, cerebral oximetry, and transcranial Doppler ultrasound) vs. Absence of neuromonitoring was evaluated on Incidence of serious brain injury (p=0.03). Multimodality neuromonitoring during coronary artery bypass grafting was associated with a reduced incidence of serious brain injury compared to no monitoring (3.0% vs 6.1%; P=0.03).
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