Key result
Delayed laparoscopic adrenalectomy after alpha and beta blockade resolves ECMO-requiring pheochromocytoma-induced cardiogenic shock.
Why the study?
Clear management guidelines are lacking due to the clinical rarity of pheochromocytoma crisis presenting with cardiogenic shock requiring ECMO.
Case Report (n=1)
In cases of pheochromocytoma-induced cardiogenic shock requiring ECMO, delaying surgical resection until after cardiac stabilization with alpha and beta blockade is a viable and successful management strategy.
May support delayed adrenalectomy after stabilization in pheochromocytoma shock on ECMO; hypothesis-generating, needs prospective validation.
An otherwise healthy woman in her 30s presented with cardiogenic shock and acute pulmonary oedema (APO), subsequently requiring extracorporeal membrane oxygenation (ECMO). A CT scan revealed an adrenal mass that prompted the differential diagnosis of a pheochromocytoma crisis that was later further suggested by raised plasma metanephrines. In the absence of clear guidelines due to the clinical rarity, a decision was made to delay adrenalectomy and stabilise the patient from a cardiac perspective with the view to operate after improvement of cardiac function with adequate alpha and beta blockade. Despite multiple complications, the patient was discharged from the hospital on day 32. After stabilisation and improvement of cardiac function, the patient underwent laparoscopic adrenalectomy. She was haemodynamically stable throughout the operation and was discharged on postoperative day 1 from the ICU to home. Histology confirmed the diagnosis of pheochromocytoma. She has been stable on follow-up.
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Redler et al. (2024) conducted a case report in Pheochromocytoma-induced cardiogenic shock requiring ECMO (n=1). Delayed adrenalectomy after cardiac stabilization was evaluated on Clinical recovery and successful surgical resection. Delayed laparoscopic adrenalectomy after cardiac stabilization with alpha and beta blockade was successfully performed in a patient with pheochromocytoma-induced cardiogenic shock requiring ECMO.
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