Answers are grounded in this paper and cite their sources.
Depending on the hematocrit, duplicate or triplicate determinations of serum amphotericin B concentration may be made on as little as 100 mul of capillary blood obtained by finger prick. In an accurate plate diffusion bioassay, using Paecilomyces varioti as the indicator organism, levels of the drug in the therapeutic range can be determined fast enough for clinicians to modify their next dose.
No takes yet. Share an insight, caveat, or question.
Bannatyne et al. (1977) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: