Key result
Growth hormone regulates metabolism by suppressing glucose uptake, stimulating lipolysis, and impairing insulin sensitivity.
Why the study?
Due to its complex effects, the regulation of GH secretion and its function in health and metabolic diseases remains a major research focus.
Design
Review
Authors
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Supports vigilance for insulin resistance in GH excess; leaves open targeted interventions pending prospective trials.
Growth hormone plays a critical role in metabolic homeostasis, with excess states leading to insulin resistance and diabetogenic effects, while deficiency alters lipid and glucose metabolism.
Nishad et al. (2018) conducted a review in Metabolic disorders. Growth Hormone was evaluated. Growth hormone regulates metabolic homeostasis by suppressing glucose uptake and oxidation, stimulating gluconeogenesis and lipolysis, and impairing insulin sensitivity.
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