Key result
Female sex linked to ~81% higher in-hospital mortality after isolated CABG despite similar mid-term survival.
Why the study?
Operative mortality rates after isolated conventional CABG have been reported higher in female patients than males, but some studies show equivalent early mortality, creating uncertainty about female outcomes.
Does female sex worsen early and mid-term mortality in patients undergoing isolated conventional CABG compared to male sex?
Population
1657 patients undergoing isolated conventional CABG including 361 females and 1296 males
Comparison
Female patients undergoing isolated conventional CABG vs male patients undergoing isolated conventional CABG
Design
Cohort study
Follow-up
Mean 47.51±25.06 months for females and 48.42±25.21 months for males
Authors
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May support sex-specific perioperative monitoring after CABG; leaves open confirmation and mechanisms in prospective studies.
Cohort (n=1,657)
No
Does female sex worsen early and mid-term mortality in patients undergoing isolated conventional CABG compared to male sex?
Absolute Event Rate: 5.8% vs 3.2%
p-value: p=0.029
Female patients undergoing isolated conventional CABG have higher in-hospital mortality than males, but similar mid-term survival.
Ergüneş et al. (2014) conducted a cohort in Isolated conventional coronary artery bypass grafting (CABG) (n=1,657). Female sex vs. Male sex was evaluated on In-hospital mortality (p=0.029). Female sex was associated with higher in-hospital mortality compared to male sex after isolated conventional CABG (5.8% vs 3.2%, P=0.029), but mid-term mortality was similar (6.1% vs 4.6%, P=0.272).
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