Tissue engineering of heart valves using decellularized xenogeneic or polymeric starter matrices
Key result
Tissue-engineered heart valves aim to provide growth and repair capabilities lacking in current replacements.
Structured PICO
I
Intervention
Tissue engineering of heart valves using decellularized xenogeneic or polymeric starter matrices
This review provides an overview of tissue engineering concepts for heart valves using decellularized xenogeneic or polymeric starter matrices to overcome the limitations of contemporary heart valve replacements.
Limitations
- Current limitations and future challenges prior to safe clinical application
Authors
Discussion
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Implication
May enable living valve replacements with growth potential; leaves open safe clinical translation pending resolution of current limitations.
Cite This Study
Schmidt et al. (2007) conducted a review in End-stage valvular heart diseases. Tissue engineering of heart valves using decellularized xenogeneic or polymeric starter matrices was evaluated. Tissue engineering of heart valves using decellularized xenogeneic or polymeric starter matrices aims to overcome the lack of growth and repair capabilities of contemporary replacements.