Key result
Spinal cord injury links to unexpected rhabdomyolysis and renal insufficiency driven by immobilization and hypoperfusion.
Why the study?
Rhabdomyolysis can occur after spinal cord injury without acute muscular injury, but its recognition and surveillance are not well established.
Case Report (n=1)
Highlights the need for surveillance for laboratory evidence of rhabdomyolysis in patients with neurologically complete spinal cord injuries.
May warrant rhabdomyolysis surveillance in complete spinal cord injury; leaves open need for prospective validation before practice change.
Rhabdomyolysis is commonly seen in association with multisystem trauma. We report an unexpected case of rhabdomyolysis and subsequent renal insufficiency after spinal cord injury unassociated with acute muscular injury. Immobilization, in conjunction with mild systemic hypoperfusion, was the suspected cause. Due to the likelihood of muscle catabolism, the difficulties of diagnosing soft tissue injury, and the impact of any decrease in renal reserve in patients with spinal cord injuries, surveillance for laboratory evidence of rhabdomyolysis in patients with neurologically complete spinal cord injuries appears warranted.
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Prall et al. (1995) conducted a case report in Spinal cord injury (n=1). Spinal cord injury with immobilization and mild systemic hypoperfusion was evaluated on Rhabdomyolysis and subsequent renal insufficiency. Spinal cord injury, likely due to immobilization and mild systemic hypoperfusion, can lead to unexpected rhabdomyolysis and subsequent renal insufficiency even without acute muscular injury.
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