Key result
CFD models require vessel wall elasticity and peripheral resistance to reproduce carotid Doppler flow waveforms.
Population
CFD model of blood flow in the carotid bifurcation based on in vivo ultrasound measurements
Comparison
Incorporation of vessel wall elasticity and… vs In vivo ultrasound measurements
Design
Preclinical
Authors
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Caution advised with simplified CFD carotid models; leaves open validation of elasticity and resistance parameters in human applications.
Accurate numerical reproduction of carotid Doppler flow wave forms requires the inclusion of both vessel wall elasticity and peripheral resistance in computational fluid dynamics models.
Maurits et al. (2006) studied Arterial disease. CFD model incorporating vessel wall elasticity and peripheral resistance vs. In vivo ultrasound measurements was evaluated on Doppler flow wave form reproduction (peak systolic velocities and smoothing). A CFD model incorporating both vessel wall elasticity and positive peripheral resistance was required to numerically reproduce experimentally obtained Doppler flow wave forms in the carotid bifurcation.
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