Why the study?
The effect of blood rheology on hemodynamic parameters such as wall shear stress and vorticity in the human carotid artery requires investigation.
Population
Patient-specific human carotid artery model segmented from MRI
Comparison
Non-Newtonian (Carreau-Yasuda) model vs Newtonian model
Design
Computational Fluid Dynamics numerical study
Key result
The non-Newtonian Carreau-Yasuda model demonstrated significant spatial variations in Wall Shear Stress compared to the Newtonian model, which undervalued WSS in regions of flow recirculation and stenosis.
Authors
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Non-Newtonian rheology may refine carotid CFD WSS estimates; hypothesis-generating, no practice change without human validation.
Computational fluid dynamics modeling demonstrates that incorporating non-Newtonian blood rheology is important for accurately estimating wall shear stress in carotid arteries, especially near plaques and bifurcations.
Nitesh Kumar (2021) studied Carotid artery stenosis and hemodynamics (n=1). Non-Newtonian (Carreau-Yasuda) blood viscosity model vs. Newtonian blood viscosity model was evaluated on Wall Shear Stress (WSS) and vorticity. The non-Newtonian Carreau-Yasuda model demonstrated significant spatial variations in Wall Shear Stress compared to the Newtonian model, which undervalued WSS in regions of flow recirculation and stenosis.
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