Key result
Ipsilateral DVT recurrence, age, obesity, previous chronic venous disease, and proximal DVT location are key predictive factors for developing post-thrombotic syndrome.
Why the study?
Despite increasing knowledge regarding DVT treatment, post-thrombotic syndrome rates remain high, and predicting which individual DVT patients will develop post-thrombotic syndrome remains difficult.
What are the predictive factors and effective prevention methods for post-thrombotic syndrome in patients with deep vein thrombosis?
What are the predictive factors and effective prevention methods for post-thrombotic syndrome in patients with deep vein thrombosis?
This review highlights that preventing ipsilateral DVT recurrence is critical for avoiding post-thrombotic syndrome, alongside identifying high-risk patients based on clinical factors.
Despite an increasing knowledge and experience regarding deep vein thrombosis (DVT) treatment, the rate of post-thrombotic syndrome (PTS) remains still relatively high. According to the current knowledge it is still difficult to predict on the individual basis, who of the DVT patients will develop PTS as late complication of the vein thrombosis. Among the factors influencing the higher prevalence of PTS, the ipsilateral DVT recurrence is of the highest importance. The other factors which should be mentioned are age, obesity, previous chronic venous disease as well as a proximal DVT location or lack of symptoms’ resolution in the early treatment. Looking for the most effective PTS prevention method several clinical trials were performed regarding pharmacological DVT treatment, use of early mobilization and medical compression stocking as well as an implementation of the thrombectomy and thrombolysis. This paper presents a review of the current knowledge regarding the PTS predictive factors and prevention.
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Tomasz Urbanek (2019) conducted a review in Deep vein thrombosis (DVT) and post-thrombotic syndrome (PTS). Predictive factors and prevention methods for post-thrombotic syndrome was evaluated on Post-thrombotic syndrome (PTS) development. Ipsilateral DVT recurrence, age, obesity, previous chronic venous disease, and proximal DVT location are key predictive factors for developing post-thrombotic syndrome.
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