Alkaline phosphatase and acid phosphatase levels in saliva and serum of patients with healthy periodontium, gingivitis, and periodontitis before and after scaling with root planing: A clinico-biochemical study

Pradeep Koppolu; Sunkara Sirisha; Ashank Mishra; Kopparesh Deshpande; Dalal H. Alotaibi; Mohammed Saleh Alwahibi; Soumya Penela

doi:10.1016/j.sjbs.2020.10.016

October 14, 2020Saudi Journal of Biological SciencesOpen Access

Alkaline phosphatase and acid phosphatase levels in saliva and serum of patients with healthy periodontium, gingivitis, and periodontitis before and after scaling with root planing: A clinico-biochemical study

View Full Paper

Ask AI

Bookmark

Share

Key Points

To correlate alkaline phosphatase (ALP) and acid phosphatase (ACP) levels in saliva and serum among patients with healthy periodontium, gingivitis, and chronic periodontitis before and after nonsurgical periodontal therapy.
Enrolled 135 subjects aged 20 to 55 years categorized into three cohorts: healthy periodontium (Group A), gingivitis (Group B), and chronic periodontitis (Group C).
Assessed clinical parameters (plaque index, gingival index, probing depth, and attachment levels) and analyzed saliva and serum ALP and ACP levels via autoanalyzer at baseline and four weeks post-scaling and root planing (SRP).
Clinical plaque and gingival indices significantly decreased post-SRP in both gingivitis and periodontitis groups, with significant reductions in probing depth and attachment loss in periodontitis.
Mean salivary and serum ALP levels and mean serum ACP levels exhibited a statistically significant decrease in both gingivitis and periodontitis cohorts following SRP.
Mean salivary ACP levels showed a statistically significant reduction post-SRP exclusively in the chronic periodontitis cohort.

No abstract yet

We only have this paper's title and publication details.

Read it at the source

Implication

Clinical study demonstrates reduced salivary and serum phosphatase levels following scaling and root planing in periodontal disease, indicating their potential as monitoring biomarkers.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Koppolu et al. (2020) studied this question.

synapsesocial.com/papers/6aa87cb2ed57a7b7cb59fd6c https://doi.org/10.1016/j.sjbs.2020.10.016

View Full Paper

Ask AI

Bookmark

Share

Alkaline phosphatase and acid phosphatase levels in saliva and serum of patients with healthy periodontium, gingivitis, and periodontitis before and after scaling with root planing: A clinico-biochemical study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Alkaline phosphatase and acid phosphatase levels in saliva and serum of patients with healthy periodontium, gingivitis, and periodontitis before and after scaling with root planing: A clinico-biochemical study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Keep reading

Keep reading