Key result
Oral infection with Col.SK virus during gestation in 100 mice resulted in only 18 viable litters, equally divided between 25 surviving and 75 deceased mothers.
Oral infection of pregnant mice with Col.SK virus results in a low rate of viable litters, regardless of maternal survival.
Low viable litters after gestational Col.SK infection in mice; hypothesis-generating for viral effects on pregnancy and requires translational validation.
From 100 mice, orally infected with Col.SK virus at various times during the period of gestation, only 18 viable litters were obtained. These litters were equally divided among 25 surviving animals and 75 animals which succumbed to the disease.
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Alice W. Knox (1950) studied this question. Oral infection with Col.SK virus during gestation in 100 mice resulted in only 18 viable litters, equally divided between 25 surviving and 75 deceased mothers.
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