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April 27, 2006HeartOpen Access

Reverse remodelling in heart failure with cardiac resynchronisation therapy

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Key result

CRT effectively treats systolic heart failure and is associated with LV reverse remodeling.

Why the study?

Left ventricular remodelling in systolic heart failure leads to poor prognosis, and the concept of reverse remodelling with cardiac resynchronisation therapy is relatively new.

Does cardiac resynchronisation therapy promote reverse remodelling in patients with chronic, severe, systolic heart failure?

Population

Patients with chronic, severe, systolic heart failure

Design

Review

Authors

MSMartin St-John SuttonUniversity of Pennsylvania Health SystemMKMartin KeaneStructural Heart Disease

Discussion

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Implication

May support CRT consideration in systolic HF; extends review evidence on reverse remodelling yet leaves selection and durability open.

Structured PICO

Does cardiac resynchronisation therapy promote reverse remodelling in patients with chronic, severe, systolic heart failure?

P
Population
Patients with chronic, severe, systolic heart failure
I
Intervention
Cardiac resynchronisation therapy (CRT)
O
Outcome
Reverse remodelling of the left ventriclesurrogate

Cardiac resynchronisation therapy is an effective treatment for chronic, severe, systolic heart failure that promotes reverse left ventricular remodelling.

Cite This Study

Sutton et al. (2006) conducted a review in Chronic, severe, systolic heart failure. Cardiac resynchronisation therapy (CRT) was evaluated. Cardiac resynchronisation therapy is an effective treatment for systolic heart failure and is associated with reverse remodelling of the left ventricle.

synapsesocial.com/papers/6aa896a53e4fe24db96536bdhttps://doi.org/10.1136/hrt.2005.067967

Topics

Heart failureHFrEF treatment
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