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September 1, 2003European Heart JournalOpen Access

Dobutamine echocardiography: a diagnostic tool comes of age

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Key result

Myocardial Doppler velocity during DSE achieves up to ~93% sensitivity for detecting CAD.

  • n=289

Why the study?

Does myocardial Doppler velocity during dobutamine stress echocardiography accurately detect coronary artery disease in patients referred for chest pain?

Population

289 subjects from eight European centres

Comparison

Objective assessment of coronary artery disease… vs Coronary angiography

Design

Editorial

Authors

DPDon PoldermansUniversità Cattolica del Sacro Cuore

Discussion

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Implication

May support quantitative Doppler in dobutamine stress echo for CAD; leaves open prospective validation before practice change.

Structured PICO

Does myocardial Doppler velocity during dobutamine stress echocardiography accurately detect coronary artery disease in patients referred for chest pain?

P
Population
An editorial discussing the MYDISE study, which evaluated myocardial Doppler velocity during dobutamine stress echocardiography in 289 subjects for the objective assessment of coronary artery disease.
E
Exposure
Objective assessment of coronary artery disease using myocardial Doppler velocity during dobutamine stress echocardiography (DSE)
C
Comparator
Coronary angiography (as reference standard in the validation group)
O
Outcome
Sensitivity and specificity for the detection of coronary artery disease (LAD, LCX, and RCA disease)surrogate

Tissue Doppler imaging during dobutamine stress echocardiography provides a sophisticated, quantitative approach with high sensitivity and specificity for detecting coronary artery disease.

Limitations

  • Subjective visual wall motion score leads to limited reproducibility.
  • Tissue Doppler velocity is influenced by the motion of adjacent segments and by translation and rotation of the heart.
  • Subjective visual wall motion score leads to limited reproducibility
  • Tissue Doppler velocity is influenced by the motion of adjacent segments and by translation and rotation of the heart

Cite This Study

Don Poldermans (2003) conducted an editorial in Coronary artery disease (n=289). Myocardial Doppler velocity during dobutamine stress echocardiography vs. Coronary angiography was evaluated on Detection of coronary artery disease. Myocardial Doppler velocity during dobutamine stress echocardiography achieved high sensitivity (80-93%) and specificity (80-82%) for detecting coronary artery disease.

synapsesocial.com/papers/6aa8a2510f6bc4a3ec653764https://doi.org/10.1016/s0195-668x(03)00343-9

Topics

Cardiomyopathy
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Feasibility of Ultrasonic Regional Strain and Strain Rate Imaging in Quantifying Dobutamine Stress Echocardiography2003 · 32 citations
  2. 2Non-invasive diagnosis of coronary artery disease by quantitative stress echocardiography: optimal diagnostic models using off-line tissue Doppler in the MYDISE study2003 · 163 citations
  3. 3Doppler tissue velocity sampling improves diagnostic accuracy during dobutamine stress echocardiography for the assessment of viable myocardium in patients with severe left ventricular dysfunction2000 · 75 citations
  4. 4Refinements in stress echocardiographic techniques improve inter-institutional agreement in interpretation of dobutamine stress echocardiograms2002 · 143 citations
  5. 5Quantitative Techniques for Stress Echocardiography: Dream or Reality?2002 · 17 citations