Key result
Highest EZSCAN quintile linked to ~108% higher dysglycemia risk versus the lowest quintile.
Why the study?
Does EZSCAN testing improve the screening and detection of prediabetes and diabetes in adults aged 40 and older?
Cross-Sectional (n=5,824)
No
Does EZSCAN testing improve the screening and detection of prediabetes and diabetes in adults aged 40 and older?
EZSCAN values higher than 30% indicate an increased risk of prediabetes and diabetes, though its incremental clinical value over conventional risk factors remains limited.
EZSCAN may flag dysglycemia risk in adults ≥40; cross-sectional data leave open incremental value over standard screening and require prospective validation.
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Yang et al. (2013) conducted a cross-sectional in Prediabetes and Diabetes (n=5,824). EZSCAN sudomotor function test (highest quintile) vs. Lowest quintile of EZSCAN value was evaluated on Presence of dysglycemia (prediabetes or diabetes) (OR 2.08, 95% CI 1.67-2.58, p=<0.0001). The highest quintile of EZSCAN value was associated with a significantly increased risk of dysglycemia compared to the lowest quintile (OR 2.08), with a 30% cut-off providing 70.3-83.7% sensitivity.
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