Key result
Patients with established rheumatoid arthritis have a higher cardiovascular morbidity and mortality compared with the general population due to accelerated atherogenesis.
Rheumatoid arthritis is an independent risk factor for cardiovascular disease, highlighting the importance of understanding how RA therapies impact accelerated atherogenesis.
Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and mortality in comparison with the general population. It is considered to be an independent risk factor for cardiovascular disease. The purpose of this article is to describe the mechanisms responsible for accelerated atherogenesis in RA patients and to give an overview of the effects of different RA therapies (methotrexate, TNF antagonists and other biologicals).
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Puttevils et al. (2014) conducted a review in Rheumatoid arthritis. Rheumatoid arthritis and RA therapies vs. General population was evaluated. Patients with established rheumatoid arthritis have a higher cardiovascular morbidity and mortality compared with the general population due to accelerated atherogenesis.
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