Key result
Aerobic training lacks sufficient evidence for mitigating treatment-related adverse CV effects in Hodgkin lymphoma survivors.
Why the study?
Hodgkin lymphoma survivors remain at increased risk for cardiovascular morbidity and mortality due to long-term cardiotoxicity of treatment, and the safety and efficacy of aerobic training on cardiovascular outcomes in this population have not been well studied.
Does aerobic training prevent cardiovascular morbidity and mortality in Hodgkin lymphoma survivors?
Does aerobic training prevent cardiovascular morbidity and mortality in Hodgkin lymphoma survivors?
This review highlights the potential role of aerobic training in mitigating cardiovascular toxicity in Hodgkin lymphoma survivors, an area with currently limited evidence.
Evidence for aerobic training in HL survivors remains limited; leaves open whether it safely reduces treatment-related CV risk.
Hodgkin lymphoma (HL) outcomes have improved due to advances in cancer treatment. However, HL survivors remain at increased risk for cardiovascular (CV) morbidity and mortality related to the long-term cardiotoxicity of HL treatment, particularly anthracycline chemotherapy and mediastinal radiotherapy. The role of aerobic training for the prevention of CV disease in the general population has been well established. However the safety and efficacy of aerobic training on CV outcomes has not been well studied in HL survivors. The purpose of this paper is to provide an up-to-date summary of the treatment-related adverse CV effects in HL survivors, review the CV benefits of exercise and review the limited evidence on the potential CV benefit of aerobic training in HL survivors.
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Yu et al. (2015) conducted a review in Hodgkin lymphoma. Aerobic training was evaluated. This review summarizes the treatment-related adverse cardiovascular effects in Hodgkin lymphoma survivors and highlights the limited evidence regarding the potential cardiovascular benefits of aerobic training.
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