Key result
ESC guidelines prioritize validated hs-cTn rule-out/rule-in algorithms for safe and rapid AMI diagnosis.
Why the study?
The widespread use of high-sensitivity assays detecting very low cardiac troponin levels presents a clinical challenge for proper test result interpretation in suspected acute myocardial infarction.
High-sensitivity cardiac troponin rule-in/rule-out algorithms recommended by the ESC allow for rapid and safe triage of patients presenting with chest pain.
May aid hs-troponin interpretation via ESC algorithms in chest pain; leaves open need for local validation studies.
Bolesti na hrudi jsou jednĂm z vedoucĂch dĹŻvodĹŻ nĂĄvĹĄtÄv urgentnĂho pĹĂjmu a hlavnĂm symptomem akutnĂho infarktu myokardu (AIM). ZĂĄkladem diagnostiky AIM je stanovenĂ hodnoty biochemickĂ˝ch markerĹŻ srdeÄnĂ ischemie v krvi. AktuĂĄlnĂm zlatĂ˝m standardem je srdeÄnĂ troponin. RozĹĄĂĹenĂ vysoce senzitivnĂch metod umoĹžĹujĂcĂch detekci velmi nĂzkĂ˝ch hodnot srdeÄnĂho troponinu pĹedstavuje vĂ˝zvu pro sprĂĄvnou interpretaci vĂ˝sledkĹŻ. DoporuÄenĂŠ postupy EvropskĂŠ kardiologickĂŠ spoleÄnosti upĹednostĹujĂ pouĹžitĂ validovanĂ˝ch algoritmĹŻ rule out/rule in k rychlĂŠmu a bezpeÄnĂŠmu vylouÄenĂ AIM a/nebo k ÄasnĂŠ identifikaci a zahĂĄjenĂ lĂŠÄby pacientĹŻ s vysokĂ˝m rizikem finĂĄlnĂ diagnĂłzy AIM. ÄlĂĄnek pĹedklĂĄdĂĄ srozumitelnĂŠ informace o vyuĹžitĂ vysoce senzitivnĂ metodiky stanovenĂ srdeÄnĂch troponinĹŻ v klinickĂŠ praxi. PĹinĂĄĹĄĂ algoritmy preferovanĂŠ Evropskou kardiologickou spoleÄnostĂ a uĹžiteÄnĂŠ informace k interpretaci vĂ˝sledkĹŻ v nÄkterĂ˝ch specifickĂ˝ch skupinĂĄch pacientĹŻ.
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Jakubo et al. (2021) conducted a review in Acute myocardial infarction. High-sensitivity cardiac troponin algorithms was evaluated. European Society of Cardiology guidelines prioritize the employment of validated rule-out/rule-in algorithms using high-sensitivity cardiac troponin to safely and rapidly diagnose acute myocardial infarction.
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