Key result
Brachial artery FMD yields >0.92 observer correlation, demonstrating acceptable reproducibility for clinical research.
Why the study?
The reproducibility and precision of flow-mediated endothelial-dependent vasodilatation (FMD) of the brachial artery need to be assessed for implementation in clinical research.
Observational (n=40)
No
Effect estimate: Correlation >0.92
p-value: p=<0.001
FMD of the brachial artery demonstrates acceptable inter- and intraobserver variability, supporting its reliable implementation in clinical research.
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FMD reproducibility assessed in 40 patients supports single-center research use; leaves open multicenter validation before broader adoption.
Simova et al. (2007) reported an observational. Flow-mediated vasodilatation (FMD) measurement vs. Independent observers and repeated measurements was evaluated on Interobserver and intraobserver variability of baseline diameter, post-ischemic diameter, and percent dilatation (Correlation >0.92, p=<0.001). Flow-mediated vasodilatation of the brachial artery demonstrated high inter- and intraobserver correlation (>0.92, P<0.001), indicating acceptable reproducibility for clinical research.
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