Key result
Fatal disseminated aspergillosis presents as purulent pericarditis in a patient with lymphosarcoma and acute leukemia.
Why the study?
Aspergillosis is an uncommon disease in humans that is increasingly recognized, typically confined to the bronchopulmonary system but occasionally becoming invasive and disseminated.
Case Report (n=1)
This case report highlights the rare occurrence of purulent pericarditis due to disseminated aspergillosis in an immunocompromised patient.
Answers are grounded in this paper and cite their sources.
Consider aspergillosis in immunocompromised patients with purulent pericarditis; leaves open optimal diagnostic and therapeutic strategies.
Case Studies1 November 1962Purulent Pericarditis in AspergillosisJOSEPH F. FRAUMENI JR., M.D., ROBERT E. FEAR, M.D.JOSEPH F. FRAUMENI JR., M.D.Search for more papers by this author, ROBERT E. FEAR, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-5-823 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough it is an uncommon disease in man, aspergillosis is being recognized with increasing frequency. The infection usually is caused byAspergillus fumigatus, and typically is confined to the bronchopulmonary system, where it appears as an abscess, granuloma, mycetoma, pneumonitis, Löffler's syndrome (1), or a condition resembling "farmer's lung" (2). On rare occasions, the infection becomes invasive and spreads hematogenously throughout the body. This report presents the clinical and pathological data of a case of fatal disseminated aspergillosis. The infection occurred in a patient with lymphosarcoma who developed an acute monocytic leukemia, and it was associated with the use of...References1. FINEGOLDDRAKEMURRAY SMWJF: Aspergillosis: a review and report of twelve cases. Amer. J. Med. 27: 463, 1959. CrossrefGoogle Scholar2. HOREJSISACHTOMSIKOVAMECL MJAA: A syndrome resembling farmer's lung in workers inhaling spores of Aspergillus and Penicillia moulds. Thorax 15: 212, 1960. CrossrefMedlineGoogle Scholar3. ZIMMERMAN LE: Fatal fungus infections complicating other diseases. Amer. J. Clin. Path. 25: 46, 1955. CrossrefMedlineGoogle Scholar4. BECH AO: Diffuse bronchopulmonary aspergillosis. Thorax 16: 144, 1961. CrossrefMedlineGoogle Scholar5. TORACK RM: Fungus infections associated with antibiotic and steroid therapy. Amer. J. Med. 22: 872, 1957. CrossrefMedlineGoogle Scholar6. 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Arch. Intern. Med. 95: 118, 1955. CrossrefGoogle Scholar19. HUNTBRODERSSTINSONCARABASI WACJCRJ: Primary pulmonary aspergillosis, with invasion of the mediastinal contents and lymph nodes. Amer. Rev. Resp. Dis. 83: 886, 1961. MedlineGoogle Scholar20. BOYLEPEARCEGUZE JPMLLB: Purulent pericarditis: review of the literature and report of eleven cases. Medicine (Balt.) 40: 119, 1961. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New YorkFrom the Department of Medicine, Memorial Hospital for Cancer and Allied Diseases, New York, New York.Requests for reprints should be addressed to Rulon W. Rawson, M.D., Memorial Hospital for Cancer and Allied Diseases, New York 21, New York. 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DUVALL, M.D., PAUL P. CARBONE, M.D.ASPERGILLUS ENDOCARDITIS AFTER OPEN-HEART SURGERYAspergillosis report of two instances in children associated with acute leukemia and review of the pertinent literature 1 November 1962Volume 57, Issue 5Page: 823-828KeywordsAcute monocytic leukemiaAspergillosisAspergillus fumigatusGranulomasHospital medicineInflammationLungsLymphomaPneumonitisStaphylococcal infection Issue Published: 1 November 1962 PDF downloadLoading ...
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Joseph F. Fraumeni (1962) conducted a case report in Disseminated aspergillosis with purulent pericarditis (n=1). Disseminated aspergillosis was evaluated. A case report describes fatal disseminated aspergillosis presenting with purulent pericarditis in a patient with lymphosarcoma and acute monocytic leukemia.
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