Key result
Baseline HR >91 bpm linked to ~100% higher risk of post-spinal hypotension vs <90 bpm.
Why the study?
Does baseline heart rate predict post-spinal hypotension in pregnant patients undergoing elective caesarean section?
Observational (n=100)
Does baseline heart rate predict post-spinal hypotension in pregnant patients undergoing elective caesarean section?
Absolute Event Rate: 50.9% vs 25.5%
p-value: p=0.0260
Pre-operative baseline heart rate >91 bpm is associated with a significantly higher risk of post-spinal hypotension in obstetric patients undergoing caesarean section.
Baseline HR >91 bpm was associated with higher post-spinal hypotension risk; leaves open whether it should guide risk stratification before prospective validation.
Background: Hypotension is a well-known side effect of spinal anaesthesia in obstetrics patients undergoing caesarean section. This is likely to affect both mother and fetal well-being. Systemic haemodynamics are modulated by autonomic nervous system (ANS). Evaluation of ANS may be helpful in predicting hypotension. The present study is designed to identify the subset of pregnant patients at higher risk of developing post-spinal hypotension based on baseline heart rate (HR) prior to administration of anaesthesia. Materials and Methods: This was a prospective study conducted on 100 patients aged 20–30 years, of American Society of Anaesthesiologists (ASA) grade I or II, scheduled for elective caesarean section under spinal anaesthesia. Patients were divided into two groups based on their baseline HR. Incidence of hypotension and ephedrine requirement following spinal anaesthesia were noted. Results: Thirty nine patients out of 100 developed hypotension (39%), of whom 27 were in the group with HR >91 beats per minute (bpm) (50.9%) and 12 patients were in the group with HR <90 bpm (25.5%). The incidence of hypotension was statistically significant between two groups (P = 0.0260). The use of ephedrine was greater in group with HR >91 bpm than group with HR <90 bpm (mean 3.9 ± 0.45 vs 4.34 ± 0.45, P = 0.0148) and it was statistically significant. Conclusion: Pre-operative baseline HR may be used to predict risk of post-spinal hypotension in obstetric patients undergoing caesarean section.
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Raghu et al. (2018) conducted an observational in caesarean section under spinal anaesthesia (n=100). Baseline heart rate >91 bpm vs. Baseline heart rate <90 bpm was evaluated on Incidence of hypotension (p=0.0260). A baseline heart rate >91 bpm prior to spinal anaesthesia for caesarean section was associated with a higher incidence of hypotension compared to a heart rate <90 bpm (50.9% vs 25.5%; P=0.0260).
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