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January 31, 2023BMC Cardiovascular DisordersOpen Access

Refractory ventricular tachycardia and heart failure due to anti-mitochondrial antibody-positive inflammatory myopathy

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Authors

RHRong HuangXZXinlin ZhangZHZhonglin Han

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Overview

Case report demonstrates clinical recovery following immunotherapy in a patient with anti-mitochondrial antibody-positive myopathy, indicating the need for targeted autoantibody screening.

Key Points

  • To describe the diagnosis and successful management of life-threatening cardiac complications in a patient with anti-mitochondrial antibody-positive inflammatory myopathy.
  • Evaluated a single patient presenting with syncope, progressive muscle weakness, muscle atrophy, and refractory ventricular tachycardia storms.
  • Administered immunosuppressive and immunomodulatory therapies after identifying anti-mitochondrial antibodies following repeated misdiagnoses.
  • Initial interventions including heart failure therapy, antiarrhythmic drugs, and an implantable cardioverter-defibrillator failed to control refractory ventricular tachycardia.
  • Treatment with combined immunosuppressive and immunomodulatory regimens halted recurrent arrhythmias and resulted in marked cardiac and clinical recovery.

Cite This Study

Huang et al. (2023) studied this question.

synapsesocial.com/papers/6aa8e579ff43606bee5d42e0https://doi.org/10.1186/s12872-023-03057-6
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