Key result
Parameter sensitivity analysis of a systemic arterial model significantly simplifies the identification scheme.
Why the study?
A parameter sensitivity analysis was needed to evaluate and improve the identification scheme for a third-order lumped-parameter systemic arterial model.
A parameter sensitivity analysis of a systemic arterial model led to a simplified and more practical identification scheme.
May streamline arterial model parameterization in research; leaves open prospective validation before clinical hemodynamic use.
An identification scheme for the determination of several parameters associated with a third-order lumped-parameter model of the systemic arterial system has been developed previously [1]. In the present study a parameter sensitivity analysis of this model is conducted in conjunction with the identification scheme. This analysis indicates that the state variables of this system are indeed sensitive to changes in the model parameters and initial conditions, but not unduly so. It also indicates the relative sensitivities of individual model parameters and provides valuable insight into the behavior of the arterial model. This insight has resulted in a significant simplification and modification of our identification scheme [1] that makes it more likely to be employed in practice.
No takes yet. Share an insight, caveat, or question.
Paulsen et al. (1982) studied Systemic arterial system modeling. Parameter sensitivity analysis and identification scheme was evaluated on Parameter sensitivity and model behavior. Parameter sensitivity analysis of a third-order lumped-parameter model of the systemic arterial system provided insight that resulted in a significant simplification of the identification scheme.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: