Key result
Careful preoperative optimization and hemodynamic control reduce the incidence of perioperative renal damage.
Why the study?
Pre-existing renal dysfunction presents specific challenges for anesthesiologists due to interactions between anesthesia and renal function that can worsen renal impairment.
Understanding the bidirectional relationship between anesthesia and renal function is crucial for perioperative renal protection in patients with pre-existing renal failure.
Answers are grounded in this paper and cite their sources.
May support perioperative renal protection in at-risk patients; hypothesis-generating and requires prospective randomized validation.
CONTEXT: Pre-existing renal dysfunction presents specific features that anesthesiologists must deal with. Anesthesia and renal function are connected and can interfere with each other. Induced hypotension anesthesia and the toxic effects of anesthetic drugs can further deteriorate renal function. EVIDENCE ACQUISITION: Decreased renal function can prolong anesthetic drug effects by decreased elimination of these drugs. Anesthesia can deteriorate renal function and decreased renal function can interfere with drug elimination leading to their prolonged effect. The anesthesiologist must understand all the physiological aspects of the patient, renal protection, and the relationships between anesthetic drugs and renal function. This review article aims to summarize these aspects. RESULTS: Perioperative renal failure and renal protection is a crucial moment in clinical practice of every anesthesiologist. CONCLUSIONS: Good knowledges for renal function remain a hallmark of daily practice of the anesthesiologist, considering renal function as an important determinant factor in anesthesia practice.
No takes yet. Share an insight, caveat, or question.
Domi et al. (2016) conducted a review in Pre-existing renal dysfunction and perioperative renal protection. Perioperative renal protection strategies was evaluated. Careful preoperative optimization, maintaining euvolemia and blood pressure, avoiding nephrotoxicity, and pharmacological protection can decrease the incidence of perioperative renal damage.
Synapse has enriched 10 related papers. Consider them for comparative context: