Key result
Adherence to four healthy lifestyles is linked to ~47% lower all-cause mortality versus none or one.
Why the study?
Little is known regarding the association between combined healthy lifestyles and mortality risk in high-risk individuals, as well as the underlying biological pathways.
Does adherence to combined healthy lifestyle factors reduce mortality in an adult general population and high-risk groups?
Population
22 839 individuals from the Moli-sani Study, including high-risk elderly, diabetic, and CVD subgroups
Comparison
Adherence to all four healthy lifestyle factors vs none or 1
Design
Prospective longitudinal cohort study
Follow-up
8.2 years
Authors
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Healthy lifestyle adherence was associated with lower mortality in high-risk groups; extends prior data but leaves open whether interventions alter outcomes.
Cohort (n=22,839)
Does adherence to combined healthy lifestyle factors reduce mortality in an adult general population and high-risk groups?
Hazard Ratio: 0.53 (95% CI 0.39–0.72)
Adherence to a combined healthy lifestyle score significantly reduces all-cause and cause-specific mortality in both the general population and high-risk subgroups.
Bonaccio et al. (2019) conducted a cohort in General population (n=22,839). Adherence to four healthy lifestyle factors vs. None or 1 healthy lifestyle factor was evaluated on All-cause mortality (HR 0.53, 95% CI 0.39-0.72). Adherence to four healthy lifestyle factors, compared with none or one, was associated with a lower risk of all-cause mortality (HR 0.53; 95% CI 0.39-0.72).
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