Key result
BAT CT radiodensity correlates with retained blood and triglycerides and is higher in active tissue.
Why the study?
The capacity of CT radiodensity to noninvasively estimate brown adipose tissue morphology and differentiate active BAT from WAT was underexplored.
Does CT radiodensity of brown adipose tissue indicate underlying tissue composition and systemic metabolic health in healthy humans?
Population
66 healthy human subjects
Comparison
BAT radiodensity with and without cold stimulus, and versus WAT
Design
Cross-sectional study with CT, PET, and 1H-MRS imaging
Authors
Loading...
CT radiodensity may reflect BAT triglyceride content and metabolic health; leaves open whether it enables noninvasive phenotyping in clinical practice.
Cross-Sectional (n=66)
Does CT radiodensity of brown adipose tissue indicate underlying tissue composition and systemic metabolic health in healthy humans?
CT radiodensity of brown adipose tissue can serve as a noninvasive marker of tissue morphology, activity, and systemic metabolic health.
U-Din et al. (2017) conducted a cross-sectional in Healthy (n=66). CT radiodensity of brown adipose tissue was evaluated on BAT radiodensity correlation with tissue morphology and metabolic health. CT radiodensity of brown adipose tissue correlated with tissue-retained blood and triglyceride content, and was higher in active BAT compared to nonactive BAT and white adipose tissue.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: