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At present, there is no effective treatment for severe ocular surface injury due to limbal stem cell deficiency.Stem cell transplantation offers hope for disease treatment, and the peripheral blood mononuclear cell fraction is a rich source of stem cells.In this study, rabbit autologous peripheral blood mononuclear cells were collected and combined with human amniotic membrane for repair of experimental ocular surface deficits.We observed good reparative effects, suggesting that autologous peripheral blood mononuclear cells are a promising stem cell source for the treatment of severe ocular surface injury.
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Zhang et al. (2020) studied this question.
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