Key result
Noninvasive vagal nerve stimulation emerges as a potential non-pharmacologic therapy for chronic abdominal pain.
Why the study?
Abdominal pain remains a major challenge and unmet clinical need, prompting interest in vagal nerve stimulation to normalize bidirectional gut-brain signaling.
Does noninvasive vagal nerve stimulation improve chronic abdominal pain in gastrointestinal disorders?
Does noninvasive vagal nerve stimulation improve chronic abdominal pain in gastrointestinal disorders?
This review highlights the potential of noninvasive vagal nerve stimulation as a non-pharmacologic therapeutic approach for chronic abdominal pain in gastrointestinal disorders.
Abdominal pain continues to be a major challenge and unmet need in clinical practice. Normalization of bidirectional gut-brain signaling has generated much interest as a therapeutic approach to treat chronic abdominal pain. Vagal nerve stimulation (VNS) is emerging as a potential non-pharmacologic strategy for the treatment of abdominal pain. In this review paper, we will summarize the etiologies of chronic pain in gastrointestinal disorders and discuss the rational for VNS as a therapeutic approach to chronic abdominal pain, with particular emphasis in the gammaCore stimulator which allows for noninvasive VNS.
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Gottfried‐Blackmore et al. (2020) conducted a review in Chronic abdominal pain in gastrointestinal disorders. Noninvasive Vagal Nerve Stimulation (gammaCore stimulator) was evaluated. Noninvasive vagal nerve stimulation, particularly using the gammaCore stimulator, is emerging as a potential non-pharmacologic therapeutic approach for treating chronic abdominal pain.
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