Key result
Roux-en-Y gastric bypass is linked to ~86% hypertension resolution in obese patients with diabetes.
Why the study?
Hypertension is common in type 2 diabetes mellitus and obesity surgery may lead to early resolution, but hypertension evolution after Roux-en-Y gastric bypass was not well described.
Does Roux-en-Y gastric bypass improve hypertension resolution in obese patients with type 2 diabetes mellitus?
Cohort (n=90)
Does Roux-en-Y gastric bypass improve hypertension resolution in obese patients with type 2 diabetes mellitus?
Roux-en-Y gastric bypass is highly effective for resolving hypertension in obese patients with type 2 diabetes.
RYGB was associated with 85.6% hypertension resolution in obese T2DM patients; leaves open whether benefits exceed optimized medical therapy.
CONTEXT: Hypertension is a common disorder in general practice and has a widely known association with type 2 diabetes mellitus. Low adhesion to clinical treatment may lead to poor results. Obesity surgery can bring early and relevant resolution rates of both morbidities. OBJECTIVE: To describe hypertension evolution after Roux-en-Y gastric bypass in patients with type 2 diabetes mellitus. METHOD: Descriptive observational study designed as a historical cohort of 90 subjects with hypertension and diabetes who underwent Roux-en-Y gastric bypass and were evaluated before and after surgery. RESULTS: It was observed a hypertension resolution rate of 85.6% along with markedly decrease in anti-hypertensive usage. Mean resolution time was 3.2 months. Resolution was associated with homeostasis model assessment - insulin resistance, preoperative fasting insulin, anti-hypertensive usage, hypertension time, body mass index and percentage of weight loss. Resolution of hypertension was not statistically associated with diabetes remission within this sample. CONCLUSION: Roux-en-Y gastric bypass was a safe and effective therapeutic tool to achieve hypertension resolution in patients who also had diabetes mellitus.
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Cazzo et al. (2014) conducted a cohort in Hypertension and type 2 diabetes mellitus in obese patients (n=90). Roux-en-Y gastric bypass was evaluated on Hypertension resolution. Roux-en-Y gastric bypass resulted in an 85.6% hypertension resolution rate at a mean of 3.2 months among obese patients with diabetes.
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