Key result
Symbolic relative entropy shows lowest ECG time irreversibility in sudden cardiac death versus normal sinus rhythm.
Why the study?
Can a symbolic relative entropy method detect differences in time irreversibility among normal sinus rhythm, ventricular fibrillation, and sudden cardiac death ECG signals?
Can a symbolic relative entropy method detect differences in time irreversibility among normal sinus rhythm, ventricular fibrillation, and sudden cardiac death ECG signals?
The symbolic relative entropy method can distinguish between normal sinus rhythm, ventricular fibrillation, and sudden cardiac death based on ECG time irreversibility, suggesting potential utility in heart disease detection.
May differentiate ECG signals by arrhythmia type; leaves open prospective validation for clinical risk stratification.
Time irreversibility of electric cardiac graph(ECG) signal can reflect the physiological function and the health condition of the heart. In this paper,we propos a symbolic relative entropy method (first symbolizing and then determining the time irreversibility) to analyze the three kinds of ECG signals, i.e., normal sinus rhythm, ventricular fibrillation and sudden cardiac death from the MIT-BIH database. The results show that three kinds of signals have different time irreversibilityies, and the time irreversibility range is largest for the normal sinus rhythm, the second largest for the ventricular fibrillation, and smallest for the sudden cardiac death. Variance test results indicate that the irreversibilities of the three signals are significantly different. The results show that the relative entropy method can play a positive role in heart disease detection and diagnosis.
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Wei et al. (2011) studied Normal sinus rhythm, ventricular fibrillation, sudden cardiac death. Symbolic relative entropy method vs. Comparison among different ECG signal types was evaluated on Time irreversibility of ECG signals. Symbolic relative entropy analysis showed significantly different time irreversibility across ECG signals, being largest for normal sinus rhythm and smallest for sudden cardiac death.
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