Key result
Continuous bilateral ESPB reduces perioperative opioid consumption versus sham in colectomy patients.
Why the study?
Colorectal surgeries cause significant postoperative pain, and effective perioperative pain management remains an anesthesiologic challenge.
Does continuous, bilateral ultrasound-guided ESPB reduce perioperative opioid consumption and improve pain scores in adult patients undergoing elective open or laparoscopic colectomy?
RCT (n=40)
Double-blind
Randomly allocated
Does continuous, bilateral ultrasound-guided ESPB reduce perioperative opioid consumption and improve pain scores in adult patients undergoing elective open or laparoscopic colectomy?
p-value: p=<0.001 for open, 0.002 for laparoscopic
Continuous bilateral ESPB effectively reduces perioperative opioid consumption and improves recovery quality in patients undergoing colorectal surgery, despite not significantly lowering postoperative pain scores.
Supports continuous bilateral ESPB to minimize opioids in colectomy; confirms efficacy in RCT for colorectal procedures.
Open and laparoscopic colorectal surgeries, while essential in the management of various colorectal pathologies, are associated with significant postoperative pain. Effective perioperative pain management strategies remain an anesthesiologic challenge. The erector spinae plane block (ESPB), a novel peripheral nerve block, has gained attention for its potential in providing analgesia for a wide variety of surgeries. This study aimed to evaluate the effectiveness of continuous, bilateral ultrasound-guided ESPB in perioperative pain management of patients undergoing colectomy. This prospective, randomized, controlled, double-blind trial included 40 adult patients scheduled for elective open or laparoscopic colectomy. Patients undergoing open colectomy as well as patients undergoing laparoscopic colectomy were randomly allocated into two groups: the ESPB group (n = 20) and the control group (n = 20). All patients received preoperatively ultrasound-guided, bilateral ESPB with placement of catheters for continuous infusion. Patients in the ESPB group received 0.375% ropivacaine, while patients in the control group received sham blocks. All patients received standardized general anesthesia and multimodal postoperative analgesia. Pain scores, perioperative opioid consumption, and perioperative outcomes were assessed. Patients in the ESPB group required significantly less intraoperative (p < 0.001 for open colectomies, p = 0.002 for laparoscopic colectomies) and postoperative opioids (p < 0.001 for open colectomies, p = 0.002 for laparoscopic colectomies) and had higher quality of recovery scores on the third postoperative day (p = 0.002 for open and laparoscopic colectomies). Patients in the ESPB group did not exhibit lower postoperative pain scores compared to those in the control group (p > 0.05 at various time points), while patients in both groups reported comparable satisfaction scores with their perioperative pain management (p = 0.061 for open colectomies, and p = 0.078 in laparoscopic colectomies). No complications were reported. ESPB is a novel and effective strategy in reducing perioperative opioid consumption in patients undergoing colectomy. This technique, as part of a multimodal analgesic plan and enhanced recovery after surgery protocols, can be proven valuable in improving the comfort and satisfaction of patients undergoing colorectal surgery.
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Sifaki et al. (2023) conducted an RCT in Colorectal surgery (n=40). Continuous, bilateral ultrasound-guided erector spinae plane block (ESPB) vs. Sham blocks was evaluated on Perioperative opioid consumption (p=<0.001 for open, 0.002 for laparoscopic). Continuous, bilateral ultrasound-guided ESPB significantly reduced intraoperative and postoperative opioid consumption compared to sham blocks in patients undergoing colectomy (p<0.001 and p=0.002).
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