What is the clinical evidence from this study?

Study design: Case Report. Population: Intracardiac mass / Metastatic lung cancer (n=1).

What does this research mean for the field?

A large left ventricular mass presenting with atypical symptoms such as groin pain can be a manifestation of metastatic lung cancer with multiple organ involvement. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe an atypical presentation of metastatic lung cancer characterized by a large left ventricular mass and multi-organ dissemination.

September 15, 2026European Heart Journal Supplements

A Surprising Intracardiac Mass, What Should We Expect?

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Key result

Metastatic lung cancer presents as a large LV mass and groin pain in a 60-year-old woman.

Population

A 60-year-old woman presenting with groin pain radiating to the lumbar region

Design

Case report

Authors

ACA CapoferriUniversity of Bergamo GDG DogniniUniversity of Bergamo RSR SanvitoUniversity of Bergamo

Discussion

Member takes

Implication

Consider metastatic lung cancer in unexplained cardiac masses; extends known metastatic patterns but remains hypothesis-generating.

Key Points

To describe an atypical presentation of metastatic lung cancer characterized by a large left ventricular mass and multi-organ dissemination.
Clinical evaluation and diagnostic workup of a 60-year-old female presenting with gait disturbance and groin-lumbar pain.
Diagnostic assessments included chest computed tomography, transthoracic echocardiography, cardiac MRI, brain imaging, and histopathological biopsies of cervical lymph nodes and subcutaneous lesions.
Imaging revealed an excavated lesion in the left lower pulmonary lobe alongside a 5 x 3 cm non-pedunculated, adherent mass attached to the interventricular septum and lateral ventricular wall.
Cardiac MRI confirmed metastatic myocardial and secondary atrial infiltration, while neuroimaging identified concurrent cerebral metastases requiring urgent radiotherapy.
Biopsies of neck lymph nodes and subcutaneous back lesions confirmed the definitive diagnosis of primary lung adenocarcinoma.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 60-year-old woman presenting with an intracardiac mass diagnosed as metastatic lung cancer.

This case demonstrates that metastatic lung cancer can present with unexpected intracardiac masses, highlighting the importance of multimodality imaging in diagnosis.

Cite This Study

Capoferri et al. (2026) conducted a case report in Intracardiac mass / Metastatic lung cancer (n=1). A 60-year-old woman presenting with groin pain was found to have a large left ventricular mass, which was ultimately diagnosed as metastatic lung cancer with multiple organ involvement.

synapsesocial.com/papers/6aa9017deed42882c1fc18df https://doi.org/10.1093/eurheartjsupp/suag058.323

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A Surprising Intracardiac Mass, What Should We Expect?

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

A Surprising Intracardiac Mass, What Should We Expect?

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider