Key result
Diabetes is linked to ~0.25 mm greater mean CIMT versus non-diabetic controls.
Why the study?
Diabetes mellitus is a major cardiovascular risk factor associated with accelerated atherosclerosis, and carotid intima-media thickness is a validated sonographic marker of subclinical atherosclerosis.
Does diabetes mellitus increase carotid intima-media thickness compared to non-diabetic controls?
Cross-Sectional (n=184)
No
Does diabetes mellitus increase carotid intima-media thickness compared to non-diabetic controls?
Absolute Event Rate: 0.87% vs 0.62%
p-value: p=<0.001
Diabetic adults have significantly higher carotid intima-media thickness than non-diabetics, supporting the use of carotid ultrasound as a non-invasive tool for early detection of subclinical atherosclerosis.
Background: Diabetes mellitus is a major cardiovascular risk factor and is associated with accelerated atherosclerosis. Carotid intima-media thickness (CIMT) is a validated sonographic marker of subclinical atherosclerosis. Methods: This hospital-based cross-sectional comparative study involved 184 adults: 92 diabetic participants and 92 non-diabetic controls. Carotid ultrasonography was used to measure right and left common carotid artery intima-media thickness (CCA-IMT) and internal carotid artery intima-media thickness (ICA-IMT). Mean values were compared using independent-samples t tests. Results: The cumulative mean CIMT was significantly higher in diabetic participants than in non-diabetic controls (0.87 ± 0.41 mm vs 0.62 ± 0.10 mm; p < 0.001). Right and left CIMT values were also significantly higher in the diabetic group. Thickened CIMT (≥1.0 mm) was more frequent among diabetics than non-diabetics (16/92 [17.4%] vs 1/92 [1.1%]; p = 0.002). Conclusion: Diabetic adults had significantly higher CIMT than non-diabetic adults, supporting the use of carotid ultrasound as a non-invasive tool for early detection of subclinical atherosclerosis in diabetes.
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Rabi'u et al. (2026) conducted a cross-sectional in Diabetes mellitus (n=184). Diabetes mellitus vs. Non-diabetic controls was evaluated on Cumulative mean carotid intima-media thickness (CIMT) (p=<0.001). Diabetes mellitus was associated with a significantly higher cumulative mean carotid intima-media thickness compared to non-diabetic controls (0.87 mm vs 0.62 mm, p < 0.001).
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