Key result
Clinical and laboratory findings associated with von Willebrand's disease can be mimicked by an intrinsic platelet defect, termed pseudo-von Willebrand's disease.
Highlights evidence that clinical and laboratory findings associated with von Willebrand's disease can be mimicked by an intrinsic platelet defect.
It is now recognized that von Willebrand's disease, a disorder characterized by a long bleeding time and reduced factor VIII, is a frequent cause of a mild hemorrhagic diathesis.1 Recent studies of the structure and function of factor VIII have provided some understanding of the abnormal hemostasis in patients with this disease, and it is apparent that several different defects in plasma can cause impaired platelet function.2 In this issue of the Journal, Weiss and his co-workers provide evidence that clinical and laboratory findings associated with von Willebrand's disease can be mimicked by an intrinsic platelet defect.3 They suggest . . .
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Leon W. Hoyer (1982) conducted an editorial in Pseudo-von Willebrand's Disease. Clinical and laboratory findings associated with von Willebrand's disease can be mimicked by an intrinsic platelet defect, termed pseudo-von Willebrand's disease.
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