Key result
Implementing a syncope protocol is linked to ~10% more successful diagnoses but higher patient costs.
Why the study?
The efficacy of a protocol to improve diagnosis and management of syncope was uncertain.
Does a standardized syncope protocol improve diagnostic rates in patients presenting with syncope?
Cohort (n=1,081)
No
Does a standardized syncope protocol improve diagnostic rates in patients presenting with syncope?
Absolute Event Rate: 78% vs 71%
p-value: p=0.003
Implementing a standardized syncope protocol improves diagnostic yield but may increase overall healthcare costs.
May improve diagnostic yield in syncope at higher cost; leaves open cost-effectiveness and need for prospective validation.
Objectives: To assess the efficacy of a protocol designed to improve the diagnosis and management of syncope.Design: Prospective outcome analysis of all patients presenting with syncope for the 12 month period from 1 November 2000 to 31 October 2001, compared with a retrospective study of all patients presenting with syncope during the calendar year 1998.Use of the protocol commenced in September 2000.Setting: Eastbourne District General Hospital, serving a population of approximately 250 000; 25% are older than 65 years.Subjects: 421 consecutive patients presenting with syncope, investigated prospectively in January 2000 and compared with 660 patients retrospectively analysed for the calendar year 1998.Results: In 1998, 71% of patients with syncope received a diagnostic classification.In January 2000 there was an appropriate diagnostic hypothesis for every patient.Ultimately a diagnosis was made for 78% of patients according to accepted criteria (p = 0.003).Use of tests with the highest diagnostic effectiveness, such as tilt tests, increased in 2001 and many tests were used more appropriately (such as echocardiography).However, non-diagnostic tests were still frequently used (such as chest radiography, electroencephalography, and carotid Doppler studies).Costs of investigation and hospital stay rose from £611 to £1384 (J874 to J1980) per patient (p , 0.001), with cost per diagnosis increasing from £870 (J1245) in 1998 to £1949 (J2790) (p , 0.001).Conclusion: The syncope protocol improved diagnosis and the use of appropriate investigations.However, significant inappropriate investigation and hospital admission still occurred.The protocol allowed reliable triage of syncopal patients into high and low risk groups.
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Youngkeun Ahn (2003) conducted a cohort in Syncope (n=1,081). Syncope protocol vs. Historical standard care was evaluated on Diagnosis made according to accepted criteria (p=0.003). Implementation of a syncope protocol increased the rate of successful diagnosis from 71% to 78% (p=0.003), although it also significantly increased the cost per patient.
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