What does this research mean for the field?

Children with syndromic craniosynostosis present with severe multi-planar skeletal discrepancies, while non-syndromic craniosynostosis is primarily confined to the cranial base, and neither condition significantly alters dental maturation relative to chronological age. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To characterize craniofacial morphology and evaluate dental maturation relative to chronological age in pediatric patients with syndromic and non-syndromic craniosynostosis.

September 15, 2026Clinical and Experimental Dental ResearchOpen Access

Craniofacial Morphology and Dental Age Assessment in Pediatric Craniosynostosis: A Comparative Cross‐Sectional Study

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Authors

NRNutthakarn Ratanasereeprasert YWYanisa Wongbanthit NINarin Intarak

Discussion

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Overview

Cross-sectional study reveals severe midface hypoplasia but normal dental maturation in pediatric craniosynostosis, indicating treatment timing should depend on skeletal rather than dental...

Key Points

To characterize craniofacial morphology and evaluate dental maturation relative to chronological age in pediatric patients with syndromic and non-syndromic craniosynostosis.
Evaluated 19 pediatric patients (syndromic craniosynostosis [SC]: n = 13; non-syndromic craniosynostosis [NSC]: n = 6; mean age 9.32 ± 2.67 years) in a comparative cross-sectional design.
Assessed 17 skeletal and dental cephalometric variables against age-matched ethnic norms and calculated dental age using the modified Demirjian method calibrated with the Duangto model.
Utilized one-sample and Welch's t-tests to evaluate differences between dental age and chronological age, as well as cephalometric parameters against normative values.
Patients with SC showed significant maxillary retrusion and midface hypoplasia, with reduced SNA (73.63 ± 9.52°), ANB (-7.1 ± 10.51°), maxillary depth (79.36 ± 11.2°), and anterior cranial base length (41.47 ± 4.56 mm) versus norms (all p < 0.05).
Patients with NSC showed skeletal deviations predominantly confined to a shortened anterior cranial base (48.17 ± 5.66 mm, p < 0.05), with other skeletal metrics aligning with normative values.
Dental age did not differ significantly from chronological age in either the SC cohort (mean difference: 0.09 ± 1.50 years, p > 0.05) or the NSC cohort (mean difference: 1.23 ± 1.61 years, p > 0.05).

Cite This Study

Ratanasereeprasert et al. (2026) studied this question.

synapsesocial.com/papers/6aa913609013453be30a12e1 https://doi.org/10.1002/cre2.70445

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September 15, 2026Clinical and Experimental Dental ResearchOpen Access

Craniofacial Morphology and Dental Age Assessment in Pediatric Craniosynostosis: A Comparative Cross‐Sectional Study

View Full Paper

Ask AI

Bookmark

Authors

NRNutthakarn Ratanasereeprasert YWYanisa Wongbanthit NINarin Intarak

Discussion

Member takes

Overview

Cross-sectional study reveals severe midface hypoplasia but normal dental maturation in pediatric craniosynostosis, indicating treatment timing should depend on skeletal rather than dental...

Key Points

To characterize craniofacial morphology and evaluate dental maturation relative to chronological age in pediatric patients with syndromic and non-syndromic craniosynostosis.
Evaluated 19 pediatric patients (syndromic craniosynostosis [SC]: n = 13; non-syndromic craniosynostosis [NSC]: n = 6; mean age 9.32 ± 2.67 years) in a comparative cross-sectional design.
Assessed 17 skeletal and dental cephalometric variables against age-matched ethnic norms and calculated dental age using the modified Demirjian method calibrated with the Duangto model.
Utilized one-sample and Welch's t-tests to evaluate differences between dental age and chronological age, as well as cephalometric parameters against normative values.
Patients with SC showed significant maxillary retrusion and midface hypoplasia, with reduced SNA (73.63 ± 9.52°), ANB (-7.1 ± 10.51°), maxillary depth (79.36 ± 11.2°), and anterior cranial base length (41.47 ± 4.56 mm) versus norms (all p < 0.05).
Patients with NSC showed skeletal deviations predominantly confined to a shortened anterior cranial base (48.17 ± 5.66 mm, p < 0.05), with other skeletal metrics aligning with normative values.
Dental age did not differ significantly from chronological age in either the SC cohort (mean difference: 0.09 ± 1.50 years, p > 0.05) or the NSC cohort (mean difference: 1.23 ± 1.61 years, p > 0.05).

Cite This Study

Ratanasereeprasert et al. (2026) studied this question.

synapsesocial.com/papers/6aa913609013453be30a12e1 https://doi.org/10.1002/cre2.70445

View Full Paper

Ask AI

Bookmark