Key result
Myocardial infarction was associated with a lower average EQ-5D-5L index (0.86 vs. 0.88; P<0.001) and EQ-VAS score (69 vs. 80; P<0.001) 3 months post-discharge compared to a reference population.
Why the study?
The study aimed to compare health-related quality of life in patients who experienced myocardial infarction with a randomly selected reference population in Norway.
Does myocardial infarction reduce health-related quality of life compared to a reference population?
Cross-Sectional
Yes
Does myocardial infarction reduce health-related quality of life compared to a reference population?
Absolute Event Rate: 0.86% vs 0.88%
p-value: p=<0.001
Patients who experienced a myocardial infarction have a significantly lower health-related quality of life at three months post-discharge compared to the general population, with women and NSTEMI patients reporting worse outcomes.
Background: The Norwegian Myocardial Infarction Registry collects patient-reported data on health-related quality of life three months after discharge from the hospital. The aim of the study is to compare health-related quality of life in patients who have experienced myocardial infarction with a randomly selected reference population in Norway. Material and method: Patients registered in the Norwegian Myocardial Infarction Registry in the period 2020-2023 and a reference population in Norway were sent a health-related quality of life questionnaire covering five dimensions (EQ-5D-5L). Health-related quality of life was measured using the EQ-5D-5L index, which ranges from 0 to 1, and EQ-VAS, which is a visual analogue scale ranging from 0 to 100. Higher values indicate a higher quality of life. Results: Patients who had experienced myocardial infarction reported a lower average EQ-5D-5L index (0.86 vs. 0.88; p < 0.001) and a lower average EQ-VAS score (69 vs. 80; p < 0.001) compared to the reference population. After myocardial infarction, women reported a poorer quality of life than men (average EQ-5D-5L index 0.82 (women) vs. 0.87 (men); p < 0.001), and patients with non-ST-elevation myocardial infarction (NSTEMI) had a lower index than patients with ST-elevation myocardial infarction (STEMI) (0.85 vs. 0.88; p < 0.001). Interpretation: Health-related quality of life was poorer in patients who had experienced myocardial infarction compared to the general population in Norway. Following myocardial infarction, women had a poorer health-related quality of life than men, and patients who had experienced NSTEMI had a poorer health-related quality of life than those who had experienced STEMI.
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Govatsmark et al. (2025) conducted a cross-sectional in Myocardial infarction. Myocardial infarction vs. Reference population was evaluated on EQ-5D-5L index (p=<0.001). Myocardial infarction was associated with a lower average EQ-5D-5L index (0.86 vs. 0.88; P<0.001) and EQ-VAS score (69 vs. 80; P<0.001) 3 months post-discharge compared to a reference population.
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