In-hospital case fatality rates for acute myocardial infarction in Romania
Key result
Female sex linked to ~33% higher risk of in-hospital death after STEMI versus men.
- OR 1.33
- 95% CI 1.13-1.56
- P<0.001
- n=9,186
Why the study?
In-hospital case-fatality rates and treatment patterns for acute myocardial infarction in an unselected Romanian population were not well described.
What are the clinical characteristics, treatments, and in-hospital case-fatality rates for patients with STEMI in Romania, and how do they differ by sex?
Population
9,186 consecutive patients admitted for STEMI in 7 tertiary referral and 21 county hospitals in Romania
Design
Prospective cohort study from the Romanian Registry for STEMI
Follow-up
In-hospital
Authors
Discussion
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Member takes
Implication
High in-hospital STEMI mortality with low reperfusion rates signals urgent systems gaps in Romania; leaves open sex-specific outcome drivers for prospective study.
Study Design
Type
Cohort (n=9,186)
Multicenter
Yes
Structured PICO
What are the clinical characteristics, treatments, and in-hospital case-fatality rates for patients with STEMI in Romania, and how do they differ by sex?
P
Population
9,186 consecutive patients admitted for ST-segment elevation acute myocardial infarction across 28 hospitals in Romania.
O
Outcome
In-hospital deathhard clinical
Main Result
Odds Ratio: 1.33 (95% CI 1.13–1.56)
p-value: p=<0.001
In a Romanian registry of STEMI patients, reperfusion therapy rates were low and in-hospital mortality was high (12.7%), with women experiencing significantly higher adjusted mortality than men.
Cite This Study
Tatu-Chiţoiu et al. (2009) conducted a cohort in ST-segment elevation acute myocardial infarction (n=9,186). Female sex vs. Male sex was evaluated on In-hospital death (OR 1.33, 95% CI 1.13-1.56, p=<0.001). Women admitted for ST-segment elevation myocardial infarction had a higher risk of in-hospital death than men after adjusting for confounders (OR 1.33; 95% CI 1.13-1.56; p<0.001).