What is the clinical evidence from this study?

Study design: Cohort. Population: Cardiac surgery (n=5318). Intervention: Major non-cardiac complications vs. Fewer or no complications. Primary outcome: Perioperative mortality (p=<0.001).

What does this research mean for the field?

Major non-cardiac complications occur in 15.9% of cardiac surgery patients and are associated with a 17.0% perioperative mortality rate that increases substantially with the number of complications. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

May 10, 2013Interactive Cardiovascular and Thoracic SurgeryOpen Access

Impact of major non-cardiac complications on outcome following cardiac surgery procedures: logistic regression analysis in a very recent patient cohort†

Q: What are the key findings of this study?

Major non-cardiac complications following cardiac surgery were associated with a perioperative mortality of 17.0%, which increased significantly with the number of complications (P<0.001).

Q: What does this research mean for the field?

Major non-cardiac complications occur in 15.9% of cardiac surgery patients and are associated with a 17.0% perioperative mortality rate that increases substantially with the number of complications. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Major non-cardiac complications post-cardiac surgery are linked to ~17% perioperative mortality, rising with complication count.

P<0.001
n=5,318

Why the study?

What is the impact of major non-cardiac complications on perioperative mortality and length of stay in adult patients undergoing cardiac surgery?

Population

5318 consecutive adult patients undergoing cardiac surgery from January 2009 to May 2012, mean age 68.9±11.0…

Design

Cohort

Follow-up

perioperative

Authors

PRParwis B. RahmanianCardiac Surgery AKA KrönerUniversity Hospital Cologne GLGeorg LangebartelsUniversity of Cologne

Discussion

Member takes

Implication

May inform perioperative risk stratification; leaves open whether preventing non-cardiac complications improves survival.

Study Design

Type

Cohort (n=5,318)

Structured PICO

What is the impact of major non-cardiac complications on perioperative mortality and length of stay in adult patients undergoing cardiac surgery?

Population

5,318 adult patients undergoing cardiac surgery, retrospectively analyzed to determine the impact of major non-cardiac complications on perioperative mortality.

Exposure

Cardiac surgery

Outcome

Perioperative mortality and hospital length of stayhard clinical

Main Result

p-value: p=<0.001

Major non-cardiac complications after cardiac surgery significantly increase perioperative mortality and length of stay in a dose-dependent manner, which can be accurately predicted using a logistic regression model.

Cite This Study

Rahmanian et al. (2013) conducted a cohort in Cardiac surgery (n=5,318). Major non-cardiac complications vs. Fewer or no complications was evaluated on Perioperative mortality (p=<0.001). Major non-cardiac complications following cardiac surgery were associated with a perioperative mortality of 17.0%, which increased significantly with the number of complications (P<0.001).

synapsesocial.com/papers/6aa914d2e4e7b17765d91b04 https://doi.org/10.1093/icvts/ivt149

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Impact of major non-cardiac complications on outcome following cardiac surgery procedures: logistic regression analysis in a very recent patient cohort†

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Cite This Study

Impact of major non-cardiac complications on outcome following cardiac surgery procedures: logistic regression analysis in a very recent patient cohort†

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Also Consider