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•Modiyinji et al. report viral hepatitis in Yellow fever suspected cases in Cameroon, underscoring the diagnostic complexity of febrile jaundice.•Molecular assays add critical specificity and genotype-level insights to outbreak surveillance.•Integration of hepatitis testing into Yellow fever surveillance would improve accuracy and align with World Health Organization's hepatitis elimination targets.•Table 1 illustrates the broader differential diagnosis of febrile jaundice, supporting the case for integrated algorithms.
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Thanchonnang et al. (2025) studied this question.
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